NAD+ AND IT ROLE IN ANTI-AGEING AND HEALTH:
One of the most exciting scientific discoveries in modern skincare and anti-aging medicine involves a molecule called NAD⁺ (nicotinamide adenine dinucleotide), a naturally occurring molecule that plays a critical role in maintaining cellular energy, in DNA repairs which has quickly become a focus of longevity and cellular rejuvenation research.
As the science evolves, one truth is becoming increasingly clear: maintaining optimal NAD⁺ levels may be one of the most powerful ways to preserve youthful, resilient skin and support whole-body wellness.
NAD⁺: A Vital Molecule for Skin and Cellular Health
NAD⁺ is a coenzyme found in every living cell, where it plays an essential role in energy metabolism, DNA repairs, immune regulation, and cellular defence against oxidative stress.
It is also the fuel behind sirtuins, a group of proteins that control how our cells respond to ageing, inflammation, and environmental damage.
At Emil Spa and Beauty Haven, we take a medically certified approach to skin restoration.We focus not only on treating visible signs of ageing but also on supporting the biological systems that maintain skin health at the cellular level. NAD⁺ is at the centre of this approach.
How NAD⁺ Decline Affects the Skin
As we age, NAD⁺ levels naturally decline a process further accelerated by environmental stressors such as sun exposure, pollution, and poor lifestyle habits. This depletion affects the skin in several ways:
Reduced DNA repair capacity, leading to genomic instability
Epigenetic changes and mitochondrial dysfunction, causing loss of cellular energy and tone
Increased inflammation and oxidative damage
Cellular senescence, where skin cells stop functioning optimally
Epigenetic changes, which alter the skin’s ability to regenerate
At Emil Spa, we often see the visible effects of these internal changes: fine lines, laxity, hyperpigmentation, delayed healing, and a general loss of vitality. Science shows that supporting NAD⁺ levels can help slow or even reverse many of these signs.
The Science Behind NAD⁺ and Skin Regeneration
The skin is particularly sensitive to NAD⁺ decline because it is in a constant state of renewal and repair. Repeated UV(ultraviolet) exposure causes DNA damage that must be repaired promptly to prevent premature ageing. Critical enzymes like PARP1(poly ADP ribose) and SIRT1/SIRT6 (Sirtuin1 &6)are responsible for this repair, but they require adequate NAD⁺ to function.
As NAD⁺ drops with age:
DNA repair slows down
Collagen synthesis is impaired
Skin structure begins to degrade
Matrix metalloproteinases (MMPs), especially MMP-1, become more active and break down collagen
Senescent (aged, inactive) skin cells accumulate.
Epidermal thinning and weakened barrier function set in
This cascade results in a visibly aged appearance, but it also makes the skin more vulnerable to further damage. However, restoring NAD⁺ levels has been shown to reverse many of these effects, improving collagen production, reducing inflammation, and enhancing the skin’s natural repair systems.
Cellular Senescence and NAD⁺
Cellular senescence is one of the core biological drivers of skin ageing. NAD+ focus on advanced skin diagnostics and therapies that aim to reduce the burden of senescent cells and reactivate healthy cellular function.
Senescent cells, particularly in aged fibroblasts and keratinocytes, no longer produce the structural proteins that give skin its firmness and elasticity. They release harmful inflammatory signals (known as the senescence-associated secretory phenotype, or SASP), which degrade the surrounding tissue and accelerate ageing.
NAD⁺ depletion worsens this process by reducing SIRT1 activity, which in turn decreases p63,(tumour protein) a protein essential for maintaining keratinocyte proliferation. When NAD⁺, SIRT1, and p63(tumour protein 63)are all diminished, the skin’s Regenerative abilities significantly decline.
NDA+ tailored protocols support these pathways through scientifically informed rejuvenation techniques that help restore cellular energy and reverse senescence-driven damage.
Epigenetic Regulation and the NAD⁺-Sirtuin Connection
Ageing is not just about DNA damage it’s also about how genes are expressed. This is known as epigenetic ageing, and it’s increasingly used to measure biological age with tools like DNA(Deoxybonucelic acid) methylation clocks. Enzymes called sirtuins, particularly SIRT1(Sirtuin1) and SIRT6(sirtuin6), are central to regulating these age-related epigenetic changes, and their activity is directly linked to NAD⁺ availability.
In skin, these sirtuins:
Support collagen synthesis
Reduce the expression of genes that degrade skin structure like MMP-1(matrix metalloproteinase-1)
Accelerate wound healing
Improve the function of keratinocytes and fibroblasts.
Unfortunately, sirtuins are downregulated as NAD⁺ declines. That’s why restoring NAD⁺ is now being studied not just as an anti-aging intervention but as a way to reset the skin’s epigenetic code.
At Emil Spa, we embrace this science to create intelligent, age-aware skincare protocols that nurture the skin from its deepest layers outward.
Targeting NAD⁺ for Visible and Lasting Skin Renewal.
Therapies that increase NAD⁺ whether through oral supplementation, lifestyle optimization,
Clinical-grade Aesthetic treatments, are becoming central to integrative skin care and longevity medicine.
At Emil Spa and Beauty Haven, we offer advanced treatments designed to:
Stimulate your body’s natural NAD⁺ production
Enhance mitochondrial and metabolic health in skin cells
Activate collagen remodelling
Improve skin density, elasticity, and hydration
Reduce inflammatory markers that contribute to ageing.
We also guide clients in choosing NAD⁺- supporting supplements such as NMN or NR, and we incorporate NAD⁺-boosting wellness strategies into our personalized treatment plans.
Where Science Meets Beauty: Your NAD⁺ Journey at Emil Spa.
The cumulative research is clear: NAD⁺ is an indispensable molecule for skin longevity, repair, and resilience. Declining NAD⁺ is no longer just a biological fact it’s a target for effective intervention.
At Emil Spa and Beauty Haven, we are proud to stay ahead of the curve, integrating this groundbreaking science into our regenerative therapies.
If you’re ready to support your skin on a cellular and regenerative level where true transformation begins, our expert team is here to guide you.
Embrace the Future of Skin Science
Discover NAD⁺-informed skin renewal with Emil Spa and Beauty Haven.
Book your consultation today and begin your journey to a radiant, resilient skin backed by biology.
To book a session with us @ Emil Spa and Beauty Haven… we amplify beauty
www.Emilspa_aesthetics. com
Call us on 07032926970 or 07051607009
Emilspa_beautyhaven @ Instagram.
#NAD+#, #AESTHETICS #, #SKIN REJUVENATION#,
NAD+ AND IT ROLE IN ANTI-AGEING AND HEALTH:
One of the most exciting scientific discoveries in modern skincare and anti-aging medicine involves a molecule called NAD⁺ (nicotinamide adenine dinucleotide), a naturally occurring molecule that plays a critical role in maintaining cellular energy, in DNA repairs which has quickly become a focus of longevity and cellular rejuvenation research.
As the science evolves, one truth is becoming increasingly clear: maintaining optimal NAD⁺ levels may be one of the most powerful ways to preserve youthful, resilient skin and support whole-body wellness.
NAD⁺: A Vital Molecule for Skin and Cellular Health
NAD⁺ is a coenzyme found in every living cell, where it plays an essential role in energy metabolism, DNA repairs, immune regulation, and cellular defence against oxidative stress.
It is also the fuel behind sirtuins, a group of proteins that control how our cells respond to ageing, inflammation, and environmental damage.
At Emil Spa and Beauty Haven, we take a medically certified approach to skin restoration.We focus not only on treating visible signs of ageing but also on supporting the biological systems that maintain skin health at the cellular level. NAD⁺ is at the centre of this approach.
How NAD⁺ Decline Affects the Skin
As we age, NAD⁺ levels naturally decline a process further accelerated by environmental stressors such as sun exposure, pollution, and poor lifestyle habits. This depletion affects the skin in several ways:
Reduced DNA repair capacity, leading to genomic instability
Epigenetic changes and mitochondrial dysfunction, causing loss of cellular energy and tone
Increased inflammation and oxidative damage
Cellular senescence, where skin cells stop functioning optimally
Epigenetic changes, which alter the skin’s ability to regenerate
At Emil Spa, we often see the visible effects of these internal changes: fine lines, laxity, hyperpigmentation, delayed healing, and a general loss of vitality. Science shows that supporting NAD⁺ levels can help slow or even reverse many of these signs.
The Science Behind NAD⁺ and Skin Regeneration
The skin is particularly sensitive to NAD⁺ decline because it is in a constant state of renewal and repair. Repeated UV(ultraviolet) exposure causes DNA damage that must be repaired promptly to prevent premature ageing. Critical enzymes like PARP1(poly ADP ribose) and SIRT1/SIRT6 (Sirtuin1 &6)are responsible for this repair, but they require adequate NAD⁺ to function.
As NAD⁺ drops with age:
DNA repair slows down
Collagen synthesis is impaired
Skin structure begins to degrade
Matrix metalloproteinases (MMPs), especially MMP-1, become more active and break down collagen
Senescent (aged, inactive) skin cells accumulate.
Epidermal thinning and weakened barrier function set in
This cascade results in a visibly aged appearance, but it also makes the skin more vulnerable to further damage. However, restoring NAD⁺ levels has been shown to reverse many of these effects, improving collagen production, reducing inflammation, and enhancing the skin’s natural repair systems.
Cellular Senescence and NAD⁺
Cellular senescence is one of the core biological drivers of skin ageing. NAD+ focus on advanced skin diagnostics and therapies that aim to reduce the burden of senescent cells and reactivate healthy cellular function.
Senescent cells, particularly in aged fibroblasts and keratinocytes, no longer produce the structural proteins that give skin its firmness and elasticity. They release harmful inflammatory signals (known as the senescence-associated secretory phenotype, or SASP), which degrade the surrounding tissue and accelerate ageing.
NAD⁺ depletion worsens this process by reducing SIRT1 activity, which in turn decreases p63,(tumour protein) a protein essential for maintaining keratinocyte proliferation. When NAD⁺, SIRT1, and p63(tumour protein 63)are all diminished, the skin’s Regenerative abilities significantly decline.
NDA+ tailored protocols support these pathways through scientifically informed rejuvenation techniques that help restore cellular energy and reverse senescence-driven damage.
Epigenetic Regulation and the NAD⁺-Sirtuin Connection
Ageing is not just about DNA damage it’s also about how genes are expressed. This is known as epigenetic ageing, and it’s increasingly used to measure biological age with tools like DNA(Deoxybonucelic acid) methylation clocks. Enzymes called sirtuins, particularly SIRT1(Sirtuin1) and SIRT6(sirtuin6), are central to regulating these age-related epigenetic changes, and their activity is directly linked to NAD⁺ availability.
In skin, these sirtuins:
Support collagen synthesis
Reduce the expression of genes that degrade skin structure like MMP-1(matrix metalloproteinase-1)
Accelerate wound healing
Improve the function of keratinocytes and fibroblasts.
Unfortunately, sirtuins are downregulated as NAD⁺ declines. That’s why restoring NAD⁺ is now being studied not just as an anti-aging intervention but as a way to reset the skin’s epigenetic code.
At Emil Spa, we embrace this science to create intelligent, age-aware skincare protocols that nurture the skin from its deepest layers outward.
Targeting NAD⁺ for Visible and Lasting Skin Renewal.
Therapies that increase NAD⁺ whether through oral supplementation, lifestyle optimization,
Clinical-grade Aesthetic treatments, are becoming central to integrative skin care and longevity medicine.
At Emil Spa and Beauty Haven, we offer advanced treatments designed to:
Stimulate your body’s natural NAD⁺ production
Enhance mitochondrial and metabolic health in skin cells
Activate collagen remodelling
Improve skin density, elasticity, and hydration
Reduce inflammatory markers that contribute to ageing.
We also guide clients in choosing NAD⁺- supporting supplements such as NMN or NR, and we incorporate NAD⁺-boosting wellness strategies into our personalized treatment plans.
Where Science Meets Beauty: Your NAD⁺ Journey at Emil Spa.
The cumulative research is clear: NAD⁺ is an indispensable molecule for skin longevity, repair, and resilience. Declining NAD⁺ is no longer just a biological fact it’s a target for effective intervention.
At Emil Spa and Beauty Haven, we are proud to stay ahead of the curve, integrating this groundbreaking science into our regenerative therapies.
If you’re ready to support your skin on a cellular and regenerative level where true transformation begins, our expert team is here to guide you.
Embrace the Future of Skin Science
Discover NAD⁺-informed skin renewal with Emil Spa and Beauty Haven.
Book your consultation today and begin your journey to a radiant, resilient skin backed by biology.
To book a session with us @ Emil Spa and Beauty Haven… we amplify beauty
www.Emilspa_aesthetics. com
Call us on 07032926970 or 07051607009
Emilspa_beautyhaven @ Instagram.
#NAD+#, #AESTHETICS #, #SKIN REJUVENATION#,